DSIP (Delta Sleep-Inducing Peptide) is a research neuropeptide consisting of eight amino acids (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu). It has been studied for its involvement in neuroendocrine regulation, sleep-related signaling, and stress adaptation through GABAergic and hypothalamic pathways. DSIP’s structure and physiological relevance make it an important subject in peptide neurobiology and circadian rhythm research.
References:
Schoenenberger GA et al., Proc Natl Acad Sci USA, 1977 74(9):4025–4029
Graf MV et al., Neuropeptides, 1984 4(3):225–238
Antonijevic I et al., J Neuroendocrinol, 1992 4(4):431–439
DSIP (Delta Sleep–Inducing Peptide) is a neuropeptide associated with sleep regulation, stress modulation, and nervous system recovery. It’s used primarily for improving deep sleep quality, calming an overactive nervous system, and helping normalize disrupted sleep patterns.
What DSIP is typically used for in research:
Falling asleep faster
Increasing deep (slow-wave) sleep
Reducing nighttime cortisol spikes
Calming “wired but tired” feeling
Supporting recovery during high stress periods



